High Profile Cannabis Shop

Columbia

1500 Interstate 70 Dr SW Suites 1,2,3, Columbia, MO 65203
(573) 844-4007
Open until 9:00pm (CT)
All hours
Mon
Tues
Wed
Thur
Fri
Sat
Sun
8:00am
-
9:00pm
8:00am
-
9:00pm
8:00am
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9:00pm
8:00am
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9:00pm
8:00am
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10:00pm
8:00am
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10:00pm
8:00am
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9:00pm

Offered at High Profile Columbia

In-store Shopping

Drop in anytime

In-store Pickup

Reserve online

Budtender Help

Call ahead or come see us

Recreational 21+

Shop with a valid ID

Medical 18+

Shop with a valid Med Card

Cash Payments

Old fashioned green

ATM Onsite

With a small fee

Pay By Bank

Link your bank at checkout online

Free Parking Lot

With plenty of spots

Wheelchair Accessible

Parking and Entrance

High Profile Columbia — Cannabis Dispensary in Columbia, MO

High Profile Columbia sits right on I-70 Drive SW near Stadium Boulevard and West Boulevard, the everyday errand corridor that CoMo locals drive without thinking about it. We’re minutes from the University of Missouri campus, downtown, and the Business Loop, so neighbors from the Old Southwest, Grasslands, and West Ash areas fold a stop into class schedules, work shifts, and grocery runs.
Regulars come from across Boone County — Mizzou and Stephens College students and faculty, south Columbia residents out by Rock Bridge, and drivers rolling in off US-63 from Ashland or in from Boonville on I-70. It’s the kind of shop where the person behind the counter recognizes the regulars and still takes time with first-timers.
Walk in and a budtender will help you work through the flower, pre-rolls, vapes, edibles, and concentrates on the menu, whether you know exactly what you want or you’re just starting out. You can reserve ahead with in-store pickup, park free in the lot out front, and pay by cash, debit, or Pay by Bank, with an ATM on site and a wheelchair-accessible entrance. Recreational shoppers 21+ with a valid ID are welcome, and medical patients are too. We’re open 8am–9pm Sunday through Thursday and 8am–10pm Friday and Saturday.

Shop at High Profile and Save

Save big every day at High Profile with competitive prices, discounted bundles, and fresh promos.

Everyday discounts available in-store

20% off

First Time Customers

With High Rollers Rewards signup

15% off

Med Patients - Mon and Tues

With valid Med Card

Veterans - Tuesdays

Thank you for your service

10% off

Industry

Current cannabis industry employees

Student / Faculty

Active students and staff

Veterans

Thank you for your service

Wisdom 60+

All customers age 60+

*Not stackable with other discounts or offers. Applicable in-store only.

Serving Boone County + Mid-Missouri

High Profile Columbia anchors the heart of Boone County and greater mid-Missouri, an easy stop for anyone moving between the college town’s south side, the Business Loop, and the surrounding US-63 and I-70 corridors. Ashland shoppers reach us in about 20 minutes up US-63, while Jefferson City is roughly a 35-minute drive north on the same highway. Coming from the east, Fulton is about 33 minutes away via I-70. Between the Mizzou campus, Rock Bridge, and the neighborhoods along Providence and Stadium, we keep the menu stocked for the everyday needs of the communities right around us.

Getting to High Profile Columbia in Columbia, MO

Ashland, MO → High Profile Columbia (~18 miles | ~20 min)

Take US-63 N to I-70 W, take exit 125 for I-70BL, then follow Interstate 70 Dr SW — we'll be right there.

Boonville, MO → High Profile Columbia (~24 miles | ~26 min)

Get on I-70 E and head toward Columbia, take exit 125, then follow Interstate 70 Dr SW — we'll be right there.

Fulton, MO → High Profile Columbia (~28 miles | ~33 min)

Take Missouri F and State Hwy J to I-70 W, continue into Columbia, then exit onto Interstate 70 Dr SW — we'll be on your right.

Jefferson City, MO → High Profile Columbia (~35 miles | ~35 min)

Take US-54 E/US-63 N out of Jefferson City, follow US-63 N to I-70 W in Columbia, take exit 125, then follow Interstate 70 Dr SW — we'll be right there.

Moberly, MO → High Profile Columbia (~36 miles | ~38 min)

Take US-63 S toward Columbia, exit onto MO-763 S, get on I-70 W and take exit 125, then follow Interstate 70 Dr SW — we'll be right there.

FAQs about High Profile Columbia

We're at 1500 Interstate 70 Dr SW, Suites 1, 2 & 3, Columbia, MO 65203, on the south frontage road just off I-70 Exit 124 (Stadium Boulevard). There's a free parking lot right out front.

We're open 8am–9pm Sunday through Thursday and 8am–10pm on Friday and Saturday.

No — recreational customers 21+ with a valid government-issued ID are welcome, and medical patients are too.

Yes. You can reserve your order online ahead of time and pick it up in store, or drop in and shop with a budtender's help.

The menu covers a wide selection of flower, pre-rolls, vapes, edibles, and concentrates from a rotating lineup of brands, with daily deals in store.

Still have a question? Reach out.
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About High Profile

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Columbia

1500 Interstate 70 Dr SW Suites 1,2,3, Columbia, MO 65203
(573) 844-4007
8am - 9pm CT Sun - Thurs., 8am - 10 pm CT Fri - Sat.
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Columbia

Columbia

Open until 9:00pm (CT)
1500 Interstate 70 Dr SW Suites 1,2,3, Columbia, MO 65203
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