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Because the store sits right on the I-70 spine through St. Charles County, it pulls easily from the communities that ring it. St. Peters is about 4 miles east, O’Fallon roughly 7 miles west, and shoppers from Cottleville, Dardenne Prairie, Lake Saint Louis, and Wentzville all reach it in well under half an hour. It is a genuinely central spot for the fast-growing suburbs strung along I-70 between St. Charles and Wentzville — the heart of one of Missouri’s fastest-growing counties. St. Charles County shoppers who plan to hit more than one dispensary in a trip will find High Profile the natural first stop — our menu is stocked for the kind of full-basket run that makes the most of Missouri’s purchasing limits.
Walk in and a budtender helps you fast, whether you know exactly what you want or you would rather talk through flower, pre-rolls, edibles, vapes, and concentrates. High Profile St. Charles is licensed for both recreational and medical sales, so any adult 21 and over shops with a valid ID while Missouri medical patients keep their patient pricing at the same counter. In-store shopping, in-store pickup, and a drive-thru window for online pre-orders keep it quick for the after-work crowd.


With High Rollers Rewards signup

With High Rollers Rewards signup

With valid Med Card

Thank you for your service

Current cannabis industry employees

Active students and staff

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All customers age 60+
High Profile St. Charles serves St. Charles County and the western St. Louis metro from its spot in the Harvestowne corridor off I-70. St. Peters is only about 4 miles east on Mid Rivers Mall Drive, roughly a 7-minute drive, and O’Fallon sits about 7 miles west, close to 11 minutes via I-70 and Highway K. Downtown St. Charles and Historic Main Street are about 5 miles away over Highway 94, and the growing communities of Cottleville, Dardenne Prairie, and Lake Saint Louis all fall within a 15-minute reach. With St. Charles County’s 400,000 residents spread across the I-70 corridor west of the city, the store is positioned at the center of one of the most populated suburban stretches in Missouri.
High Profile St. Charles is at 1416 Harvestowne Industrial Dr, St. Charles, MO 63304, in the Harvestowne industrial corridor just off I-70 with a free parking lot on site.
The store is open Sunday through Thursday from 8am to 9pm and Friday and Saturday from 8am to 10pm, with the drive-thru and in-store shopping available during all open hours.
No — any adult 21 and over with a valid government-issued ID can shop recreationally, though Missouri medical patients can use their card for patient pricing.
Yes, in-store pickup is available for online pre-orders alongside walk-in shopping and a drive-thru window.
The menu spans flower, pre-rolls, edibles, vapes, and concentrates across a range of price points, with budtenders on hand to help you choose.




By selecting 'Yes', you confirm that you are of legal age or a valid medical patient and agree to our Terms and Privacy Policy.
